A bone marrow biopsy is done for diagnosing blood disorders. This usually includes study of chromosomes (cytogenetics) and examination of the surface proteins or receptors on the bone marrow cells through the process of flow cytometry. Treatments of blood disorders vary depending on the type of disease and may include use of steroids and other immune-modulating therapies, transfusions or coagulation factor support, growth factor supplementation, complex chemotherapy and bone marrow transplantation. Palliative care is one of the most specialised approach which provide medical care for people who suffer from serious illness. Anticoagulants (antithrombics) are a class of drugs that work to prevent the coagulation which are used in hemodialysis machine, Heart-lung machine, etc. One type of vascular filter called the vena cava filter is implanted by interventional radiologists or vascular surgeons into the inferior vena cava to prevent life-threatening pulmonary emboli with the use of ionizing radiation, generally, as part of cancer treatment to manage and control malignant cells. Most of the hematologist prefer physical examinations, medical history and laboratory testing to detect hematological diseases or disorders of the patient.
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Blood is a living tissue which consists of liquid and solid. The liquid part is plasma containing water, salts and protein and the solid part containing red blood cells, white blood cells and platelets. Blood disorders affect one or more parts of the blood and can be acute or chronic. Many blood disorders are also inherited. Haemophilia A is a genetic disorder with the deficiency of clotting factor VIII. The second-most common form of haemophilia is Hemophilia B, a blood clotting disorder caused by mutation of the factor IX gene, leading to deficiency in its factor IX. Rare haemophilia is Hemophilia C which affects both male and female. However, it most commonly occurs in Jews of Ashkenazi descendants which is also most famously known as fourth coagulation disorder after von Willebrand's disease and haemophilia A and B.
In USA, it is thought to affect 1 in 100,000 of the adult population. Idiopathic thrombocytopenic purpura (ITP) is defined as isolated low platelet count (thrombocytopenia) with normal bone marrow and absence of other causes of thrombocytopenia. It is also known as immune thrombocytopenia or primary immune thrombocytopenia or primary immune thrombocytopenic purpura or autoimmune thrombocytopenic purpura. The most common disease described in humans is Von Willebrand disease which is a hereditary coagulation abnormality. Platelets are also known as "thrombocytes" and its function (along with the coagulation factors) is to stop bleeding by clumping and clogging blood preventing blood vessel injuries.
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#Cancers are recognized due to the #signs or #symptoms that occur after a particular #stage or through #screening. Neither of these leads to exact #diagnosis of the #disease and its type, it mainly requires examination of a #tissue sample obtained generally by #biopsy, by a #pathologist. #Cancer can be treated by many methods such as #surgery, #chemotherapy, #hormonal_therapy, #radiation_therapy, #targeted_therapy and #synthetic lethality. People suffering from #Cancer can be investigated through #medical_tests which includes #blood_tests, #X-rays, #CT_scans and #endoscopy. The #tissue #diagnosis from the #biopsy indicates the type of #cell that proliferates through its #histological grade, #genetic_abnormalities and other features. All together it gives useful information about the #molecular changes such as #mutations, #fusion #genes and numerical #chromosome to estimate the #prognosis inorder to choose the best #treatment. #Cytogenetics and #immunohistochemistry are the other common #tissue #tests. The removal of #cancer without damaging the other parts of the #body (by achieving cure with near-zero adverse effects) is the main goal of the #treatment. The type of #treatment depends on the type of #cancer the #patient is suffering from and its #stage. Most of the people with #Cancer have a combination of #treatments such as #surgery with #chemotherapy or #radiation_therapy, #Immunotherapy, #targeted_therapy or #hormone_therapy.
Explore new trends in #Cancer #diagnosis and #treatment at World Hematology 2019 on July 23-24, 2019 at #Rome, #Italy, PS: https://hematology.cmesociety.com/call-for-abstracts

#Oncogenomics is a field in #genomics which characterize #cancer-associated #genes. Its main focus includes #genomic, #epigenomic and #transcript #alterations in #cancer. The main concept and idea of #oncogenomics is to check new group of #oncogenes or #tumour_suppressor_genes that may give new areas of #research into #cancer_diagnosis, predicting #clinical outcome of #cancer_treatment and new #targets for #cancer_therapies. The #Gleevec, #Herceptin and #Avastin are the targeted #cancer_therapies which gave a new way for #oncogenomics to elucidate new targets for #cancer_treatment. #Metabolomics is a newly emerging field in 'omics' #research and refers to the complete set of small-molecule #metabolites, which gives the systematic study of unique chemical #fingerprints that leaves #cellular processes behind. The #metabolome represents the collection of all #metabolites in a #biological_cell, #tissue, #organ or an #organism that are the end products of #cellular_processes. #Metabolic_profiling gives an instantaneous snapshot of the #physiology of given #cell. One of the challenging aspects of system #biology and functional #genomics is to integrate #proteomic, #transcriptomic and #metabolomic information which provide a better understanding of #cellular #biology.
Explore more about #Hematology_Oncology and unleash the enigma in #Hematology and #Oncology through #WorldHematology2019 on #July 23- 24, 2019 at #Rome, #Italy #Hematology_Conferences, #Cancer_Conferences, #Oncology_Conferences, #Blood_Conferences, #Blood_Disorders_Conferences, #Internal_medicine_Conferences, #Cancer_research_Conferences, #Pulsus_Conferences
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Medical Oncology is the type of cancer treatment where drugs are used to destroy cancer cells. Medical Oncologist’s purpose is to deliver the best outcome for cancer patients providing palliative care. Chemotherapy uses anti-cancer drug stopping the growth of cancer cells. It also harms the cells which are healthy such as those that line the mouth and intestines. Side effects generally occur while dispensing Chemotherapy. So neoadjuvant therapy can be given before surgery to reduce the risks. Clinical Oncology is the sort of Cancer treatment in which doctors use Chemotherapy as well as Radiotherapy to treat patients. Technologies are nowadays developing rapidly in the field of Clinical Oncology, for example: some tumours can be treated with highly sophisticated external beam radiation therapy such as Proton beam therapy.
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#Surgical_oncology comes under the field of #surgery applied to #oncology, which involves the #surgical_management of #tumours, mainly #cancerous_tumours. The goals of the #surgical_oncologist includes the removal of #cancerous_cells and keeping an area of #healthy_tissue surrounding it, also known as a clear margin or clear excision in order to prevent the #cancer recurring in that area. Sometimes it's difficult to remove the whole #tumor, therefore, a debulking #surgery can be done to remove as much #tumour as possible and to relieve #symptoms such as #pain, #airway_obstruction and #bleeding. #Surgical_oncologists are also called as general surgical oncologists, #thoracic_surgical_oncologists, subspecialty of general surgery, #gynecologic_oncologists, etc who are experienced in treating the #cancer_patients. The James Ewing Society is recognised today as the Society of Surgical Oncology which was started by the surgeons interested in initiating and promoting the field of #oncology. Complex General Surgical Oncology was given by American Board of Surgery, specially ratified as specialty Board certification in the year 2011.
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Contact: Vijaya L
Program Manager | World Hematology 2019
worldhematology@pulsusmeet.com | worldhematology@pulsusevents.net